VolumeVol. 62 • Number No. 2 • April - June 2024 Back
Comparison of Clinical Outcomes and Presence of Nephropathy and/or Retinopathy Among Type 2 Diabetes Mellitus Patients with Obesity and Overweight versus those with Normal Body Mass Index: A Cross-Sectional Study
Authors: Jennifer Lourdes Ng, Janine Audrei Pajimna, Margaret Encarnacion-Fernandez, Sweet Garllie Albert Tappan, Gabriel Jasul Jr., Oliver Allan Dampil
DOI: 10.65564/pjim.b1d6d28663
Date of Publication: June 2024
Abstract
Background: This study aimed to determine the differences in glycemic control, metabolic parameters (blood pressure control, triglycerides, LDL, HDL) and the presence of nephropathy and/or retinopathy between obese and overweight versus normal body mass index (BMI) type 2 diabetes mellitus patients (T2DM).
Methodology: This is an analytic cross-sectional study of T2DM patients from outpatient clinics at St. Luke’s Medical Center, Quezon City. Available medical records and laboratory tests were reviewed. Data were analyzed and compared between those overweight and obese versus those with normal BMI based on Asia Pacific Guidelines.
Results: A total of 248 patients with T2DM were included in the study. More patients who are obese and overweight have uncontrolled diabetes (p = 0.011), low HDL (p = 0.037) and nephropathy (p = 0.027) compared to those with normal BMI. There were no significant difference between overweight and obese patients versus those with normal BMI with regards to BP control, high LDL, high triglycerides and retinopathy.
Conclusion: T2DM patients who are obese and overweight have a significantly higher prevalence of uncontrolled diabetes, low HDL and nephropathy compared to those with normal BMI.
Keywords: Diabetes Mellitus, Obese, Overweight, Nephropathy, Retinopathy
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